Male circumcision may protect against HPV infection in males and females CMIJournal hpv HPV protection sexualhealth health news immunology microbiology
By Dr. Sanchari Sinha Dutta, Ph.D.Apr 10 2023Reviewed by Lily Ramsey, LLM A systematic review and meta-analysis published in the Clinical Microbiology and Infection Journal highlights the protective effect of male circumcision on the prevalence, incidence, and clearance of human papillomavirus infection in males and their female sexual partners.
Many studies have found a link between male circumcision and reduced risk of human immunodeficiency virus infection, herpes simplex virus type 2 infection, syphilis, genital ulcer, chancroid, and candidiasis. For the risk of bias assessment, the Newcastle-Ottawa scale and the Cochrane risk-of-bias tool were used for observational studies and randomized trials, respectively.
Prevalence of HPV infection The prevalence of HPV infection among all participants at baseline ranged from 8.7% to 69.8%. 21 studies reported the association between circumcision and HPV infection prevalence in males.
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