Study reveals SARS-CoV-2 on hands and frequently-touched surfaces as key predictors of household transmission SARSCoV2 Coronavirus Disease COVID LancetMicrobe UKHSA imperialcollege
Study: Risk factors and vectors for SARS-CoV-2 household transmission: a prospective, longitudinal cohort study. Image Credit: cunaplus / Shutterstock
In the current study, scientists have explored whether the presence of SARS-CoV-2 on the hands of infected household members and on frequently-touched surfaces can predict the household transmission of the virus. Important observations A total of 414 household contacts, including 152 PCR-positive and 262 PCR-negative contacts, from 279 households were included in the study analysis. The majority of study participants were unvaccinated. Among all household contacts, 134 had longitudinal serological data and were included in the serology subgroup. None of the participants in this group was vaccinated against COVID-19.
The analysis of hand- and surface-collected samples revealed that the respiratory viral load of primary cases is associated with the detection of viral RNA on their hands. However, no correlation was observed between their respiratory viral load and household infection rate. Study significance The study reveals an infection rate of approximately 52% among predominantly unvaccinated and infection-naïve household contacts exposed to alpha variant-infected primary cases.
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