Population, Clinical, and Scientific Impact of National Cancer Institute's National Clinical Trials Network Treatment Studies | Journal of Clinical Oncology

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Population, Clinical, and Scientific Impact of National Cancer Institute's National Clinical Trials Network Treatment Studies | Journal of Clinical Oncology
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Four decades of clinicaltrials: 14.2 million life-years gained, at $326 per year

Additionally, projected estimates for 2025 and 2030 were based only on currently identified trials, with no attempt made to model how many studies will be positive in the future. From all of these perspectives, our estimate of life-years gained is likely conservative.

In conclusion, the NCI-sponsored NCTN groups represent a vital and durable element of the scientific infrastructure of cancer clinical research in the United States. Randomized trials conducted by NCTN groups have contributed substantial gains in life-years for patients with cancer, and the studies have had a marked impact on cancer treatment guidelines and the scientific literature.

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