Police were called to a report that a group were chased on foot by a car.
Police were called to a report that a group of three or four men all dressed in black, were being chased by a car in Kirkby, Merseyside, at around 8.50pm on Friday, July 14.
Officers are currently carrying out door-to-door enquiries and appealing for CCTV in a bid to identify the offenders. Cordons remained in place on neighbouring streets on Saturday, July 15, reports the Liverpool Echo. Top news stories today “We have a zero-tolerance approach to any person involved in the use of, possession of, and storage of firearms, and we will relentlessly pursue anyone involved in this type of awful criminality.
“We will always take immediate action to incidents involving guns and we are actively working to make Merseyside a safer place to live and work. Information from the public is vital if we are to breakdown the organised crime groups who bring misery to our streets.
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Effects of intravenous administration of magnesium sulfate in propofol-based sedation for ERCP in elderly patients: a randomized, double-blind, placebo-controlled study - BMC GeriatricsBackground Propofol-based sedations are widely used in elderly patients for endoscopic retrograde cholangiopancreatography (ERCP) procedure, but respiratory depression and cardiovascular adverse events commonly occur. Magnesium administered intravenously can alleviate pain and decrease propofol requirements during surgery. We hypothesized that intravenous magnesium was used as adjuvant to propofol might be beneficial in elderly patients undergoing ERCP procedures. Methods Eighty patients aged from 65 to 79 years who were scheduled for ERCP were enrolled. All patients were intravenously administered 0.1 µg/kg sufentanil as premedication. The patients were randomized to receive either intravenous magnesium sulfate 40 mg/kg (group M, n = 40) or the same volume of normal saline (group N, n = 40) over 15 min before the start of sedation. Intraoperative sedation was provided by propofol. Total propofol requirement during ERCP was the primary outcome. Results The total propofol consumption were reduced by 21.4% in the group M compared with the group N (151.2 ± 53.3 mg vs. 192.3 ± 72.1 mg, P = 0.001). The incidences of respiratory depression episodes and involuntary movement were less in the group M than those in the group N (0/40 vs. 6/40, P = 0.011; 4/40 vs. 11/40, P = 0.045; respectively). In the group M, the patients experienced less pain than those in the group N at 30 min after the procedure (1 [0–1] vs. 2 [1–2], P | 0.001). Correspondingly, the patients’ satisfaction was clearly higher in the group M (P = 0.005). There was a tendency towards lower intraoperative heart rate and mean arterial pressure in group M. Conclusions A single bolus of 40 mg/kg of intravenous magnesium can significantly reduce propofol consumption during ERCP, with higher sedation success and lower adverse events. Trial Registration ID UMIN000044737. Registered 02/07/2021.
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