Catheter ablation is a safe and effective treatment for atrial fibrillation in patients with a history of cancer and those with exposure to potentially cardiotoxic therapy, finds a study published in Cardio-Oncology.
]. Patients with cancer, particularly those exposed to potentially cardiotoxic antineoplastic therapies, are at a higher risk of developing AF and subsequent cardiomyopathy and HF and catheter ablation may provide a promising treatment option for selected patients. In addition to symptomatic improvement, catheter ablation may alleviate the need for ongoing AAD therapy thus limiting serious drug-drug interactions.
Cancer-specific characteristics such as type of malignancy, presence of metastatic disease, active cancer therapy, systemic chemotherapy or surgery in the 5 years prior to ablation, radiation therapy, anthracycline exposure, cancer status at the time of ablation, and cancer recurrence after ablation were also obtained. The CHA-VASc score was used to calculate stroke risk. Anticoagulation with either warfarin or direct oral anticoagulants was also recorded.
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