Study identifies enzyme that helps tumors evade the immunesystem northwesternu NatureComms
is lost, remains to be determined.
In summary, this work proposes a rationale and preclinical evidence to combine Checkpoint 1/2 inhibition with PD-1/PD-L1 blockade, to enhance the responsiveness of gliomas to immune checkpoint blockade therapy.All mice were housed at the Center for Comparative Medicine at Northwestern Feinberg School of Medicine. Mice were housed in a conventional barrier facility with 12-h light/12-h dark cycles and ad libitum access to food and water.
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