Zebrafish are marvelous creatures. Not only are they completely see-through, but they can also grow new organs. We already knew these translucent little fish could regenerate retinal tissue in their eyes – now new research shows how zebrafish can
that help the human heart patch itself up after a heart attack.with an mRNA technique that delivers genetic instructions to heart muscle cells to repair themselves.
They discovered three types of fibroblasts temporarily entered an activated state, switching on genes that encode muscle-building proteins such as collagen XII, whichAnd when the researchers 'silenced' those genes in the zebrafish, their hearts could no longer regenerate.of the collagen-expressing fibroblasts.
Single-cell sequencing techniques, the likes of which the researchers used in this study to locate heart cells sending out regenerative signals, are at the forefront of fast-advancing genomic technologies.
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