After a series of medical breakthroughs, will these animals solve the global shortage of organs?
Using animal organs in the human body isand has ranged from "zest for life" chimpanzee testicle implants to replacement kidneys and hearts taken from our primate relatives. The latter often ended in death soon afterwards. The problem is, our immune system treats the transplanted organ like an infection and attacks.
It has one genetic tweak to prevent any donated organs responding to human growth hormones and growing out of control. The resulting 10-gene pigs are then raised in sterile conditions so they are suitable for transplant.The pair of pig kidneys were transplanted into the brain-dead body of Jim Parsons in September 2021.
Their patient, David Bennett, 57, had severe heart failure. He was not deemed suitable for a human heart transplant and was being kept alive by an Ecmo machine, which supported his heart and lungs.A 10-gene pig was driven to the hospital and on 7 January, its heart was placed inside David Bennett's chest. The operation was tricky because Mr Bennett's diseased heart had swollen, so connecting the blood vessels to the smaller pig-heart was a challenge.
Mr Bennett was very frail before the operation and it is possible that even the new heart was not enough.
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