When to update COVID-19 vaccine composition. Comment from SCBriand, David E. Wentworth, Kanta Subbarao, mvankerkhove and colleagues WHO CDCgov
Immunological profiles are increasingly heterogeneous, and so the performance of an updated vaccine will vary depending on the nature and magnitude of previously acquired immunity in each person.
. So far, available vaccines with an updated composition are predominantly mRNA-based, although others are likely to follow. The paucity of data from vaccines other than those based on mRNA technology is problematic, given the diversity in vaccines in use globally.Since January 2022, there has been a substantial reduction in SARS-CoV-2 diagnostic testing and sequencing globally, as well as in the number of SARS-CoV-2 genome sequences submitted to open access databases, such as GISAID EpiCov.
Decisions on vaccine antigen composition require extensive evaluation of the neutralizing capacity of well-characterized human convalescent sera, which are obtained from naive and previously vaccinated individuals, including after infection with VOCs and descendent lineages, well-characterized panels of human monoclonal antibodies, and sera from naive, infected and vaccinated animal models.
Österreich Neuesten Nachrichten, Österreich Schlagzeilen
Similar News:Sie können auch ähnliche Nachrichten wie diese lesen, die wir aus anderen Nachrichtenquellen gesammelt haben.
Nature Medicine - COVID-19 vaccine hesitancy⚡ Our February issue is live! With research, news and opinions covering COVID19 vaccine hesitancy, CRISPR gene editing, precision diabetes, NASH, cancer clinical trials and much more. Check it out here:
Weiterlesen »
Protecting public health in Iran in the face of oppressionProtecting public health in Iran in the face of oppression. Correspondence from PardisSabeti and colleagues harvard HarvardChanSPH broadinstitute
Weiterlesen »
Genomic medicine offers diagnostic hope for people with rare diseases | Pediatric ResearchAn 18-year-old experienced symptoms of her rare disease from birth, but it wasn’t until 2020 that she got her diagnosis thanks to genomic medicine.
Weiterlesen »
‘Sleep as medicine,’ or how to make a hospital stay less unhealthySome experts say sleep deprivation is a contributor to “post-hospital syndrome” — a term for the weakened immune systems, loss of body mass and other impairments that land many people back in a hospital soon after discharge.
Weiterlesen »
Medicine-resistant fungal infection, C. auris, potentially linked to four deaths in MississippiMississippi is battling an outbreak of C. auris, a fungal infection resistant to medication, which the Department of Health says may be responsible for the deaths of four people.
Weiterlesen »
Controlled growth of perovskite layers with volatile alkylammonium chlorides - NatureNature research paper: Controlled growth of perovskite layers with volatile alkylammonium chlorides
Weiterlesen »