What We Know About Leaky Gut Syndrome

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What We Know About Leaky Gut Syndrome
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Leaky gut is a condition in which the lining of the intestines become inflamed, damaged, or irritated, allowing microbial toxins and undigested food particles to flood into the bloodstream.

—or more precisely, the inside of the gastrointestinal tract—comes in contact with items from the outside world every day.

“Leaky gut is a great visual term for patients, but it isn’t a true medical diagnosis,” says Dr. John Whyte, a board-certified internist based in the Washington, D.C., area. Rather than being a precise diagnosis, the term “describes the fact that your intestines aren’t working properly.” Symptoms often include bloating, nausea, and cramping, but “because the gut impacts our entire body, it can also cause headaches, rashes, fatigue, and joint pain,” Whyte says.

All of these symptoms overlap with other GI conditions and ailments. “You have to rule out other conditions like celiac disease, irritable bowel, or colitis” before a diagnosis of leaky gut is made, Singh says. The standard American diet is high in saturated fat, sugar, and processed foods, while low in fiber. Increasingly, studies are showing that this type of eating “is a big driver in our impaired intestinal function,” Beaulieu says. Heavy alcohol use, stress, and poor sleep also disrupt the delicate makeup of the gut, she says.

Exactly why this happens isn’t completely understood, but Singh says the normal bacteria that reside in the gut and help support a healthy immune system, proper digestion, and a range of other bodily functions tend to get replaced or lost, which causes inflammation. “Inflammation leads to symptoms or signs of leaky gut syndrome, because where there’s inflammation, that will cause increased permeability,” he says.

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