A newly disclosed cancer study had 'unprecedented' and 'unheard-of' results, and now all eyes are on dostarlimab, the GlaxoSmithKline drug used to achieve complete remission in the trial.
The term became more widely known in the last two years as a variety of monoclonal antibodies came out to treat COVID-19.
Dostarlimab is specifically designed to block a particular protein involved in cancer cells called PD-1. In the Memorial Sloan Kettering trial with rectal cancer, all of the patients' tumors also had a feature known as mismatch repair deficiency.Cells that have mutations that keep them from fixing mistakes when DNA is copied are said to have"mismatch repair deficiency."Copyright NBC New York
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