The psychedelic compound psilocybin appears to boost brain connectivity.
There may be some truth to the common saying that magic mushrooms will open up your mind. New research shows that psilocybin, the psychedelic compound naturally found in some fungi, can help patients with depression by changing their brain-wave patterns.
Participants given escitalopram reported mild improvement in their symptoms at the end of the six-week treatment. By contrast, those who were given the high dose of psilocybin reported rapid improvement in their depression. Their fMRI scans showed heightened brain connectivity—and those improvements persisted for weeks. Psilocybin creates a liberating effect in the brain, the study authors write, breaking it out of the rut of depressive thinking.
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