CRISPR-based pig meat has been given the green light by the FDA to be turned into sausages and fed to human beings.
, but it involves utilizing sterile male pigs as "surrogate sires" for selective breeding purposes. To this end, the WSU team utilized CRISPR to disable a specific gene, resulting in the males becoming sterile. They then proceeded to implant sperm-producing stem cells from a different pig into these males. As a result, the previously infertile males were able to produce offspring that carried the genes of the sperm-cell donor pig.
In theory, this method enables farmers to increase the number of offspring from a pig with several desirable characteristics beyond what is achievable with just its sperm. Thus, the valuable pig's reproductive capabilities are effectively transferred to other pigs. These pigs have since been slaughtered, with some meat sent to the FDA for investigation, and the rest turned into German-style sausages for sale.
"With this technology, we can get better dissemination of desirable traits and improve the efficiency of food production," lead researcher Jon Oatley toldin 2020. "This can have a major impact on addressing food insecurity around the world," the added. The sausage produced by the WSU team has received FDA approval as the first gene-edited meat that was not developed by a private company.
"There's a trust that comes with university-based research," said Oatley. "At WSU, we're all about the science. We just want to make sure the research is valid, and the animals we produce are healthy," they added.
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