Exposure to a traffic-related air pollutant significantly increases risk for dementia, new research suggests. MedTwitter
for dementia, but studies attempting to pinpoint its exact impact have yielded conflicting results.
Researchers analyzed data from 17 studies with a total of 91.4 million individuals, 6% of whom had dementia. In addition to PM, the investigators also assessed nitrogen oxides, which form smog, nitrogen dioxide, and ozone exposure. After adjustments for other known risk factors, such as age and gender, results showed that dementia risk increased by 3% for every 1 cubic meter rise in PMThe associations between dementia and exposure to nitrogen oxides , nitrogen dioxide and ozone did not reach statistical significance. However, the confidence intervals were wide enough that clinical relevance cannot be ruled out, Martin said.exposure affected dementia risk.
However, the clear link between fine particulate matter exposure and increased risk emphasizes the need to address air pollution as a modifiable risk factor for dementia, he added. "The rising tide of dementia is not something we can easily reverse," Martin said."The evidence has been so elusive for how to treat dementia once you have it, so our biggest opportunity is to prevent it."
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