Some studies suggest that the risk of cardiovascular problems, such as a heart attack or stroke, remains high even many months after a SARS-CoV-2 infection clears up
In December 2020, a week before cardiologist Stuart Katz was scheduled to receive his first COVID-19 vaccine, he came down with a fever. He spent the next two weeks wracked with a cough, body aches and chills. After months of helping others to weather the pandemic, Katz, who works at New York University, was having his own first-hand experience of COVID-19.
It’s a gaping hole in an important area of public health, says Katz. “We don’t understand if this changes the lifelong trajectory for risk of a heart attack or stroke or other cardiac events — we just don’t know that.” Here, Nature looks at the questions that scientists are asking and the answers they’ve uncovered so far.
Despite its large size, the VA study does come with caveats, say researchers. The study is observational, meaning that it reuses data that were collected for other purposes — a method that can introduce biases. For example, the study considers only veterans, meaning that the data are skewed towards white men. “We don’t really have any study like it that goes into more diverse and a younger population,” says Eric Topol, a genomicist at Scripps Research in La Jolla, California.
Indirect effects of the COVID-19 pandemic, such as missed medical appointments, stress and the sedentary nature of isolating at home probably further contributed to the cardiovascular burden for many people, scientists suggest.
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