BA.4.6, a subvariant of the Omicron COVID variant which has been quickly gaining traction in the US, is now confirmed to be spreading in the UK.
, early estimates suggest BA.4.6 has a 6.55 percent relative fitness advantage over BA.5 in England. This indicates that BA.4.6 replicates more quickly in the early stages of infection and has a higher growth rate than BA.5.than that of BA.5 over BA.2, which was 45 percent to 55 percent.
that people who had received three doses of Pfizer's original COVID vaccine produce fewer antibodies in response to BA.4.6 than to BA.4 or BA.5. This is worrying because it suggests that COVID vaccines might be less effective against BA.4.6., which target Omicron specifically, alongside the original strain of SARS-CoV-2. Time will tell.
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