A new survey of an under-explored aspect of human biology uncovers the many roles of the body's 'greasy molecules.'
The sequencing of the human genome promised a revolution in medicine, but scientists soon realized that a genetic blueprint alone does not show the body in action. That required understanding the proteome -- all the proteins, expressed by our genes, forming the cellular machinery that performs the bulk of the body's functions. Now, another set of molecules known as the lipidome -- all the lipids in our bodies -- is filling in more details of human physiology.
Our genome is essentially stable. Our proteome, though influenced by our health and environment, is largely dependent on what's encoded by our genes. In contrast, our lipidome can be directly altered, in part, by what we eat and which microbes live inside our gut, making it more malleable and perhaps more responsive to interventions. But the number and variety of lipid molecules -- there are at least thousands -- has made them hard to study.
The researchers found that although everyone's lipidome has a distinctive signature that remains stable over time, certain types of lipids changed predicatably with a person's health. "Every molecule that is associated with a disease has a chance of telling us more about the mechanism and may be serving as a target for affecting the disease progression," said Daniel Hornburg, PhD, a former post-doctoral scholar in Snyder's lab and co-lead author of the study.
Österreich Neuesten Nachrichten, Österreich Schlagzeilen
Similar News:Sie können auch ähnliche Nachrichten wie diese lesen, die wir aus anderen Nachrichtenquellen gesammelt haben.
Man arrested after attempting to cross the Atlantic in human hamster wheel, officials sayA unique contraption that washed up on a Florida beach revealed a bizarre story of an arrest, officials said.
Weiterlesen »
Dolphins Understand Human GazeThe ability to understand visual attention in humans is rare among animals.
Weiterlesen »
War on Terror succeeded but experts lament 'cost' of human life, 'distraction' from other threatsThe U.S. eliminated al Qaeda and shattered ISIS after the two-decade mission across the Middle East, but those successes cost many lives and distracted from other threats.
Weiterlesen »
Two San Antonio men arrested in Maverick County, face human smuggling chargesWOAI NBC News Channel 4 San Antonio provides local news, weather forecasts, traffic updates, investigations, and items of interest in the community, sports and entertainment programming for San Antonio and nearby towns and communities in South Central Texas, including Windcrest, Uvalde, Universal City, Somerset, Seguin, Schertz, San Marcos, Sabinal, Poth, Poteet, Pleasanton, Pearsall, New Braunfels, Live Oak, Kerrville, Hondo, Helotes, Goliad, Fredericksburg, Floresville, Eagle Pass, Devine, Del Rio, Cuero, Crystal City, Converse, Cibolo, Castroville, Carrizo Springs, Boerne, Bandera.
Weiterlesen »
Factbox-US, Vietnam reach deals on planes, tech and human rights as Biden visits By ReutersFactbox-US, Vietnam reach deals on planes, tech and human rights as Biden visits
Weiterlesen »
House intelligence chair calls migrant crisis ‘unbelievable human tragedy’ but also security threat“Some of them seek a better life, but some of them intend to do us harm,” GOP Rep. Mike Turner of Ohio claimed of the migrants.
Weiterlesen »