.AstraZeneca's David Fredrickson is encouraged by the latest cancer research and discusses the four Ps: Policy, Politics, Priorities, and Prevention. CancerResearch OncTwitter
JOHN WHYTE: Hi, everyone. I'm Dr. John Whyte, WebMD's chief medical officer. And you're watching Cancer in Context.
And of course, politics plays into that. But I do think that one of the core messages that we're really a part of trying to move forward-- and I think that the pandemic made this clear-- is that a healthy society contributes to a thriving economy, and that this is an investment into cancer, not just a cost that society has to bear.
JOHN WHYTE: We've had some good news lately in terms of cancer deaths. Slight decrease, typically about 1% to 2%, which can be tens of thousands of lives. But we're still having more than 600,000 people die of cancer every year. You and I were talking a little earlier, the war on cancer started in 1971 here, down at the Capitol.
JOHN WHYTE: But a war makes it sound like we're going to marshal all our resources and we're going to get this done in a relatively defined period of time.JOHN WHYTE: Is it the wrong term maybe, or where do you think we're going to be? JOHN WHYTE: So we want that earlier diagnosis. We want those targeted therapies. We want that precision medicine that you and I have talked about before. So what's the role of biomarkers in all of this, and why is it so challenging to make sure that that's democratized? So when you talk about disparities, we know there's differences in terms of who might get biomarkers, irrespective of their tumor type, based on race, ethnicity, sometimes based on gender.
DAVID FREDRICKSON: Well, we were very concerned about it, I would say, 18 months ago, and it was one of the reasons that we worked together with many, many different advocacy groups on a campaign called New Normal, Same Cancer to try to create awareness around this. I'm pleased to say that right now-- and we follow this, as you can imagine, quite closely-- I do think diagnosis rates are getting pretty back to where they were at pre-COVID levels. So it's encouraging to see that.
DAVID FREDRICKSON: Well, the origin of cancer's fiercest opponent was that the late Jose Baselga, who passed away in 2021, he was a colleague of ours. And as we lost him, we mourned that cancer had lost its fiercest opponent. And so Susan Galbraith and I, as we led from those days going forward together, it became a rallying cry for our organization. It became a rallying cry to say that we know that cancer is a disease that we believe can be defeated.
DAVID FREDRICKSON: It's a very good question. I would say that while maybe the sort of lay discourse is from a US perspective that, when I look at the way in which we approach clinical trial enrollment and what health agencies require, in Japan, Japanese patients are essential to be studied in order to be able to file in Japan. The same is true with the China FDA.
JOHN WHYTE: People are saying we want accountability. Right? We want to know that you decided upfront you're going to meet these goals and you're going to use every effort to do it, and if they're not met, there's going to be some accountability at an executive level. JOHN WHYTE: A big discussion in Washington is around payment. What do you say to those folks who say drugs are just too high, in terms of the cost?
DAVID FREDRICKSON: Yeah. Well, so there's no question that prevention is the best way to avoid disease, have lower costs, healthy society, et cetera. And I think that we know that, frankly, across so many different walks of life. In terms of what's our role, I think that there's two parts to it. First, we have been leading efforts to really make sure that, beyond our medicines, that we are focusing on early screening, early detection, early diagnosis.
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