Study in mice shows how chronic caffeine consumption alters sleep pattern and blood flow

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Study in mice shows how chronic caffeine consumption alters sleep pattern and blood flow
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A new study finds that chronic caffeine consumption has surprising effects on sleep patterns and brain blood flow in mice, increasing brain blood flow during sleep.

The study, led by Dr. Andrew Charles of UCLA, was conducted using a minimally invasive microchip and video recording system, which allowed theto remain freely moving while it recorded various physiological and behavioral parameters over extended periods, ranging from weeks to months.

The researchers found that brain blood flow was generally correlated with activity, causing it to be higher during the awake state and lower during sleep. The exception to this pattern was periods of REM sleep, during which there were large increases in brain blood flow in the absence of any movement.

Mice compensated for the delayed sleep onset by sleeping more solidly and"sleeping in." Since most individuals are not practically able to"sleep in" to compensate for delayed sleep onset, this may explain the perception that caffeine reduces sleep quality;

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