Scientists set out to map the world's genomic diversity uwmedicine nature
sciences at the University of Washington School of Medicine in Seattle and a co-author of the paper.
The human genome consists of sequence of 3.1 billion DNA molecules. Overall, our genomes are remarkably similar. But small differences in the sequences of our genomic DNA play a large role in determining what makes each individual unique, including his or her risk for disease. Earlier this spring, scientists announced that they had finished a two-decades long effort create a genome reference that represented a complete map of a human genome. Thisis a composite created from the DNA sequences of a very small group, about 20 individuals, with most of the sequence coming from a single individual. As a result, the reference does not reflect the diversity seen in the world's population.
Other populations have expressed interest, but want to do their own genome-sequencing and make the results available on their terms. The project is trying to provide these communities with the technology and skills they need to conduct this science.
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