This ability helps them colonize the brain easily.
according to a press releaseThe fungus may be found in a variety of settings and shows the same adaptability inside the body once inhaled, moving from the lungs via the bloodstream to other organs., which causes swelling of the brain in people with weakened immune systems.“Cryptococcus cells in the lungs are very diverse with different sizes and different appearances.
Previous findings show that the fungus multiplies to ten times its usual size in order to survive in the lungs, presumably growing too big for the host immune system to kill. Nevertheless, fungal cells are significantly smaller in other parts of the body. To investigate why cells of a specific size were found so deep in the host territory, the researchers infected mice with various sizes ofand found that, compared to medium and large cells, the smallest prefer infecting the brain.These small cells also differed from the others with the unique features on their surface that were similarly important for accessing the brain.
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