In a recent CDC's MMWR study, researchers found that while respiratory syncytial virus (RSV) infections are less common than COVID-19 and influenza in Americans aged 60+ years, they result in much more severe clinical outcomes. This insight supports the CDC's recommendation for RSV vaccination in older adults, emphasizing its potential in preventing severe respiratory disease.
By Hugo Francisco de SouzaOct 10 2023Reviewed by Susha Cheriyedath, M.Sc. In a recent study published in the Centre for Disease Control and Prevention's Morbidity and Mortality Weekly Report , researchers compared the prevalence and disease severity of respiratory syncytial virus infections with other common respiratory ailments, notably coronavirus disease 2019 and influenza.
RSV is a contagious pathogen, with transmission occurring mainly through infection of victims' eyes or nasal passages. Hitherto, infection treatment has been primarily supportive, involving oxygen therapy for mild cases and high-flow nasal cannula or noninvasive ventilation for more advanced infections. In life-threatening scenarios, intensive care unit admission and invasive mechanical ventilation are employed.
Between February 1, 2022, and May 31, 2023, data from adults over the age of 60 presenting respiratory ailments clinically confirmed as being RSV, COVID-19, or influenza were collected and compiled. The sample cohort focused on patients admitted to any of the 25 American hospitals participating in the Investigating Respiratory Viruses in the Acutely Ill Network.
Study findings Data collected initially comprised 6,061 elderly, of which 277 were excluded due to incomplete records. Analyses revealed that, of the remaining 5,784 patients included, 5.3% were admitted due to RSV, 81.8% due to COVID-19, and 12.9% due to influenza, highlighting the low overall prevalence of RSV amongst elderly Americans. Notably, while RSV and influenza prevalence showed a strong association with seasonality, COVID-19 prevalence remained high year-long.
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Most seniors with RSV-linked hospitalization are aged ≥75, according to researchMost respiratory syncytial virus (RSV)-associated hospitalizations among seniors aged ≥60 years occur in those aged ≥75 years, and although RSV is less common among seniors, it is associated with more severe disease than COVID-19 or influenza, according to research published in the Oct. 6 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report.
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