Researchers may have cracked why some people have long-term smell loss from COVID-19

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Researchers may have cracked why some people have long-term smell loss from COVID-19
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RALEIGH, N.C. — Last February, Ruth Sheehan recovered from a COVID-19 infection that took away her sense of smell.

Nearly two years later, her olfactory world is still dark. The smells of perfume, the Thanksgiving turkey, subtle food seasoning and coffee are similarly lost on her nostrils.

Duke researchers may have finally figured out what is happening in the noses of people like Sheehan, who never fully recover. The process is described in a paper published Wednesday in the journal “Science Translational Medicine.” “The findings appeared pretty striking to us — there really are some very obvious differences,” Goldstein said.

That inflammation could explain why the samples from the smell-loss group had substantially fewer olfactory nerve cells, the “key cells” for smelling, Goldstein said.

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