Explore the breakthrough technology of the double-barrel nanopipette and its role in understanding and treating cancer recurrence.
About 500 times thinner than human hair, the tool can help sample cancer cells individually and know what helps them escape advanced treatments.A double-barrel nanopipette, developed by a research collaboration in the UK, could help deliver valuable insights into the functioning of cancerous cells and perhaps one day find a cure for the deadly disease. The collaboration included researchers from the University of Leeds, Imperial College London, and Earlham Institute in Norwich.
A research team led by Lucy Stead, an associate professor of brain cancer biology at the University of Leeds, has now developed a nanopipette that can work at a cellular level and biopsy an individual cell to show how it responds to treatment in real time. This can be repeated to help scientists map the cell’s behavior in response to the treatment over a longer time horizon.
The nanopipette has two nanoscopic needles, injecting and extracting a sample from the cell simultaneously. Given its small size, it cannot be operated by hand but is controlled using robotic software.
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