Pfizer's child-sized vaccine fails to produce immunity in younger kids; company adds third dose to trials

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Pfizer's child-sized vaccine fails to produce immunity in younger kids; company adds third dose to trials
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Vaccine maker Pfizer says trials of its vaccine in children ages 2 to 5 show it did not provide the expected immunity in kids this age and it is adding a third dose to the regimen.

The company decided to add the third dose for all children and babies ages 6 months to 5 years after its independent outside advisers took a look at the data so far.It showed that two child-sized doses of the Pfizer/BioNtech vaccine was not producing the expected immunity in the 2- to 5-year-olds, although it was doing so for the babies up to age 2.So the company said it would"amend" the trial to add a third dose.

"The decision to evaluate a third dose of 3 micrograms for children 6 months to under 5 years of age reflects the companies' commitment to carefully select the right dose to maximize the risk-benefit profile," it added."If the three-dose study is successful, Pfizer and BioNTech expect to submit data to regulators to support an Emergency Use Authorization for children 6 months to under 5 years of age in the first half of 2022.

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