They matched 2,093 patients to find out.
Dr. Andreas Palm and colleagues looked at data from 62,811 patients five years before the start of treatment for OSA in Sweden. The scientists considered factors that could influence the results, such as body size, other health issues, and socioeconomic status,They matched 2,093 patients with OSA and a cancer diagnosis up to five years before OSA diagnosis with 2,093 patients with OSA but no cancer.
The apnoea hypopnea index , which measures the number of breathing disturbances during sleep, or the oxygen desaturation index , which measures how many times per hour levels of oxygen in the blood fall by at least 3 percent for 10 seconds or longer, were used to assess the severity of OSA.“We found that patients with cancer had slightly more severe OSA, as measured by an apnea-hypopnea index average of 32 vs. 30, and an oxygen desaturation index of 28 vs. 26,” Dr. Palm said.
“In further analysis of subgroups, ODI was higher in patients with lung cancer prostate cancer , and malignant melanoma .“The findings in this study highlight the need to consider untreated sleep apnea as a risk factor for cancer and for doctors to be aware of the possibility of cancer when treating patients with OSA. However, extending screening for cancer to all OSA patients is not justified or recommended by our study results.
Dr. Palm and his colleagues intend to expand the number of patients and follow them over time to investigate the potential effects of CPAP treatment on cancer incidence and survival.Purpose Chronic hypoxic and hypercapnic respiratory failure and obstructive sleep apnoea are chronic diseases associated with decreased quality of life and increased mortality.
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