About 700,000 people a year die from drug-resistant infections, and by 2050 it could explode to 10 million a year. But the needed medicines tend not to make money.
A dependence on only a few pharmaceutical companies to sustain the fight against superbugs is putting the world in a precarious position, a new report shows.
News from the field is grim as low profits discourage investment in crucial antibiotics. Since the group’s last report in 2018, two major players, Novartis and Sanofi, have retreated from antibiotic research as the pharma industry shifts toward lucrative areas such as cancer. And two smaller drug developers, Achaogen Inc. and Melinta Therapeutics, have filed for bankruptcy.
GlaxoSmithKline has the biggest batch of potential products, developing almost one-fifth of all the research and development projects the group identified, according to the benchmark. The report also cited Pfizer Inc., Johnson & Johnson, Entasis Therapeutics Holdings Inc. and Cipla Ltd. as some of the other leaders in the field.
A separate report last week found that research and development spending for a group of 15 companies fell to $1.2 billion in 2018 from $1.9 billion two years earlier. The research, from the AMR Industry Alliance, raises concern about a shortfall in late-stage spending in particular.The need for new antibiotics is rising along with the risks.
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