Add unprovoked VTE to the list of potential consequences of severe OSA. ERS2022
, history of cardiovascular disease, statin use, type of sleep study, study site and CPAP adherence, the investigators found that only T90 remained a significant independent predictor of VTE, with a hazard ratio of 1.06,The association between T90 and VTE strengthened as the time spent below 90% saturation increased. Patients in the highest tercile, who spent more than 6% of the time undersaturated, had an HR for VTE of 1.95 compared with patients with a T90 less than 1%.
Session co-moderator Raphael Heinzer, MD, MPH, Lausanne University Hospital, Lausanne, Switzerland, commented,"We see that T90 seems to be a strong parameter." "Obviously, there could be an influence of other hypoxic-related diseases," she said, and recommended controlling for this in future studies.
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