The research is still a ways off on having a reliable 'pill for men'
. Its superpower in the contraceptive arena is that it acts like an androgen and like a progesterone . Its presence presumably is expected to pre-empt the hormone signaling that normally would trigger sperm production. This drug hadThis is testosterone, a basic steroid hormone. The 11-beta-MNTDC molecule has a long tail added to it. Credit:The courageous volunteers in this larger safety trial who actually got the hormone took either 200 mg a day or 400 mg a day for 28 days, with food.
The last time researchers got near hormonal contraception for men, the trial of an injectable version was stopped because of side effects. Twenty participants in that study dropped out, and among the side effects were concerning signs of depression, although no one knows if mental health effects were related to the study drug. Women report all kinds of effects of hormonal contraception on their mental health, but as with so much related to women’s health, evidence one way or the other is scant.
In this most recent outing for men and hormonal contraception, the side effects did not seem to be as dire. A handful of men reported fatigue, headache, acne, or decreased sex drive, and a couple reported “mild” erectile dysfunction that apparently did not interfere with their sexual activity. There were no drug discontinuations.
That’s all promising, but less promising is a prediction from one of the study senior authors, Christina Wang, a professor of medicine atpress release from the Endocrine Society accompany presentation of the findings, Wang says that we’re looking at a 10-year wait for “safe, reversible” hormonal contraception for men. She also says that men are into having this option available, or at least about 1 in 2 men in stable relationships say that they are.
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