'Despite the lack of statistical significance, these results are clinically meaningful.'
that could save or at least help people who would today be out of options.
"When I was told about the trial, I didn't hesitate to join — what did I have to lose?" one study participant named Barry Ambrose, who had previously been told that his throat cancer was incurable because it had spread to his lungs, toldThe new treatment completely cleared the cancer from his throat after eight weeks, and subsequent chemotherapy and surgery got the cancer out of his lungs as well.
“Although I had to make biweekly trips from Suffolk to the hospital for the treatment, I had virtually no side-effects and was able to carry on as normal doing the things I love: sailing, cycling, and spending time with my family," Ambrose added. However, the drug cocktail's fate as a future clinical treatment is hazy, at best. The phase III clinical trial failed to achieve statistical significance across all patients. That's the go-to measurement clinical scientists use to determine whether or not the treatment actually had an effect or if any supposed benefits happened by pure chance.
Failing to reach that benchmark means researchers can't be sure that it was actually the new drug cocktail that eradicated those tumors. But calculations of that sort are less important to the patients, several of whom told"Despite the lack of statistical significance, these results are clinically meaningful," ICR professor of biological cancer therapies Kevin Harrington, the oncologist who led the research trial, told.
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