As people age, melanocyte cells lose motility and become stuck in the developing hair follicle compartment.
Decoding the hair cells' movementAccording to the study, these cells hone their ability to move between two compartments: germ and hair follicle bulge. In the germ compartment, melanocyte cells interact with WNT hair pigment proteins to create color.
In this continuous back-and-forth movement between the compartment, the cell's state changes from primitive to mature — known as the transit-amplifying state. Simply put, for normal hair color, these cells must be active; that is, they must constantly be moving back and forth on the maturity axis.
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