The cells are responsible for cognitive decline.
It’s all because of the APOE4 gene expressed by microglia, one of the strongest genetic risk factors for Alzheimer’s disease that makes it so that the human brain cannot metabolize lipids normally. The end result is a build-up of excess lipids that interferes with neurons’ ability to communicate with each other.
The researchers now hope that if they can restore normal lipid metabolism in microglia, they may succeed in treating some of the symptoms of the disease. So far, it has been estimated that people who carry one copy of APOE4 have a threefold higher risk of developing Alzheimer’s, and people with two copies have a tenfold higher risk.“If you look at this another way, if you look at the entire Alzheimer's disease population, about 50 percent of them are APOE4 carriers.
Österreich Neuesten Nachrichten, Österreich Schlagzeilen
Similar News:Sie können auch ähnliche Nachrichten wie diese lesen, die wir aus anderen Nachrichtenquellen gesammelt haben.
Self-boosting vaccines: An MIT invention could solve one of healthcare's biggest problemsResearchers are testing a new type of drug delivery device that stores the second dose of vaccine for a specified period before releasing the substance.
Weiterlesen »
Your Diabetes Medication Could Protect You From Developing Alzheimer’s, Study FindsResearchers think this may be a promising candidate for the treatment of Alzheimer’s disease.
Weiterlesen »
Dolphins make peace and love—not war—when they encounter strangersNew research shows a “striking” display of tranquility between animals scientists usually consider rivals.
Weiterlesen »
The Role of Visual Perception in MisophoniaIs there a sound you hate? Like chewing or slurping? Here's what we know about 'misophonia,' by ndaviden
Weiterlesen »
DMTs Significantly Cut Risk of Long-Term Disability in PPMSTreatment with disease-modifying therapies is linked to a significantly reduced risk of becoming wheelchair dependent over 10 years – but only in primary progressive MS or with inflammatory activity.
Weiterlesen »
74-year-old man suffering from diabetes, Alzheimer's disease missing in CarsonOne person died Thursday when a vehicle crashed down an embankment in the Malibu area.
Weiterlesen »