New research aims to understand the ecology of SARS-CoV-2 at the human-animal interface

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New research aims to understand the ecology of SARS-CoV-2 at the human-animal interface
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At the height of the COVID-19 pandemic, Virginia Tech disease ecologists wondered if the virus was having the same effect on wildlife.

With the support of a $5 million grant from the U.S. Department of Agriculture's Animal and Plant Health Inspection Service, principal investigator Joseph Hoyt and co-principal investigators Carla Finkielstein, Kate Langwig, and James Weger-Lucarelli will take an interdisciplinary approach to exploring the risk of SARS-CoV-2, the virus that causes COVID-19, infections in wildlife communities.

Langwig's role is to perform mathematical modeling on all the field data taken from individual wildlife communities. This includes sites with high human interaction, such as Greenway Park in Roanoke, and closed wilderness areas with limited interactions. Finkielstein is no stranger to adapting to the evolving pandemic landscape. As scientific director of the Virginia Tech Molecular Diagnostics Lab, she and her team processed between 1,600 and 2,000 COVID-19 tests a day at the facility in Roanoke during the height of the pandemic. For this study, she will use genomic approaches to discover novel variants and examine adaptation of variants to humans and animals.

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