'Just as we’ve seen a transformation in cancer treatment in recent decades, we’re really hopeful we’re on the same path for dementia.'
A new drug has been hailed as a "turning point in the fight against Alzheimer’s" after it was found to slow the progression of the disease.
Researchers examined almost 1,800 people with early-stage Alzheimer’s, half of them received a monthly infusion of donanemab and the other half were given a placebo over 18 months. The study, published in the Journal of the American Medical Association and presented to the Alzheimer’s Association International Conference in Amsterdam, concluded that after 76 weeks of treatment, donanemab was able to slow clinical decline by 35.
The company said it is ready to work with health regulators in the UK as well as the NHS and Government on the "appropriate regulatory next steps". The National Institute for health and Care Excellence said that it has already started its appraisal work on the drug. His son Mark Colley added: "I never thought I would see my dad just so full of life again. Now we have hope, a few years ago we didn’t and that is just an incredible difference."
Dr Oakley also told BBC Breakfast: "In the last 12 months we’ve had two trials, one announced last November and one this afternoon, and these trials show remove a protein called amyloid from the brain really effectively, and that seems to slow down the progression of the disease. "As a potential first-generation treatment, donanemab’s effects are modest. But these results provide further confirmation that removing amyloid from the brain can change the course of Alzheimer’s, and may help people affected by this devastating disease if they’re treated at the right time."
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