New DNA-based anticoagulant could treat heparin-induced thrombocytopenia

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New DNA-based anticoagulant could treat heparin-induced thrombocytopenia
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Various medical circumstances, including heart attacks and extreme cases of COVID-19, necessitate the use of anticoagulants, medicines that prevent blood clots

Reviewed by Lily Ramsey, LLMAug 21 2023 . But the most commonly used, heparin, can induce potentially fatal side effects by making the blood clots worse rather than better. This only happens in a minority of patients so effective treatments are not commonly explored.

Heparin was the first anticoagulant and is used widely — it's considered incredibly important by the World Health Organization. But, because of the low number of HIT sufferers and thus lack of interest from the pharmaceutical industry, this issue is underexplored, despite its severity and increase due to COVID-19. It can be especially problematic in pregnant women as they cannot take existing treatments due to those potentially adversely affecting the fetus.

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