New research shows that being infected with multiple strains of the Chagas-inducing parasite may hinder the disease's progression.
New research from Tulane University may shed light on how parasite strain diversity can impact Chagas disease progression and severity.parasites, which are transmitted by kissing bugs. In the Americas, the disease affects 6 million people in 21 countries, with approximately 30,000 new cases each year.
"Since the 1980s, researchers have proposed that different strains could be associated with different disease outcomes due to the parasite's genetic diversity, but decades of research failed to uncover clear associations," said lead study author Eric Dumonteil, PhD, associate professor of tropical medicine at Tulane University School of Public Health and Tropical Medicine.
Dumonteil said studies are ongoing to further understand the interactions of various parasite strains during infection. The study was co-authored by Dumonteil, Hans Desale, PhD, Claudia Herrera, PhDand Preston Marx, PhD, from the Department of Tropical Medicine. The research was conducted at the Tulane National Primate Research Center. Technical support was provided by medical research specialist Kelly Goff, Monica Shroyer and Weihong Tu. Nora Hernandez-Cuevas from the Autonomous University of Yucatan in Mexico collaborated in the study.
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