Monkeypox vs. Chickenpox: How to Tell the Difference

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Monkeypox vs. Chickenpox: How to Tell the Difference
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Monkeypox vs. Chickenpox: Infectious Disease Doctors Break Down the Difference

explains. It can cause an itchy, blister-like rash that usually appears on the chest, back, and face, before spreading over the entire body.

“They’re both viral infections that cause pox-like lesions,” he says. “Rarely in our lifetimes have we had we had two pox diseases co-circulating at the same time.” Chickenpox, for example, creates a “very thin-walled, fragile blister” that’s usually filled with clear fluid, Dr. Schaffner says. But monkeypox causes a “deep-seated, firm, or rubbery kind of lesion—it’s much more firm and stable than the chickenpox lesion,” he explains.

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