Monkeypox DNA hints virus has been spreading in people for years

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Monkeypox DNA hints virus has been spreading in people for years
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The virus responsible for the worldwide monkeypox outbreak may have been spreading between people a lot longer than we thought - DNA analysis suggests human-to-human spread began in 2017

, while still related to the 2017 virus. These three viruses were found in people who had travelled to different countries in Africa and the Middle East in 2021 or 2022.

Surprisingly, rather than having evolved to be fitter and better at spreading in people, the existing viruses may be less fit than the 2017 ones, because they are accumulating lots of mutations that are probably detrimental. While this is reassuring, we shouldn’t assume that monkeypox won’t evolve to be better at spreading in people if we give it a chance to do so, she says.

There were some researchers who thought the SARS-CoV-2 coronavirus wouldn’t be able to evolve into different variants in the way it is doing, says Hodcroft.

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