Mounting evidence suggests microplastics in our blood are likely capable of crossing our mammalian brain-blood barrier.
, respond to weathered polystyrene-derived microplastics compared with similarly-sized 'virgin' ones.
Making up 10 to 15 percent of brain cells, microglia patrol our central nervous system in search of objects that shouldn't be there. Unsurprisingly,Kim and colleagues found the weathered microplastics affected proteins involved in breaking down sugars into energy, increasing their expression in the microglial cells 10 to 15 times more than in cells belonging to control groups. They also increased the concentrations of proteins involved in brain cell death by a factor of 5.
This all amounts to an increased inflammatory response by brain cells – far more severe than what was produced by unweathered microplastics tested at equivalent doses.
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