Melatonin Sleep Aid May Reduce Self-Harm in Young People With Anxiety and Depression

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Melatonin Sleep Aid May Reduce Self-Harm in Young People With Anxiety and Depression
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Medical sleep treatment may reduce self-harm in young people with anxiety and depression, an observational study from Karolinska Institutet in Sweden suggests. The risk of self-harm increased in the months preceding melatonin prescription and decreased thereafter, especially in girls. The study is p

An observational study from Sweden’s Karolinska Institutet indicates that medical sleep treatment with melatonin may lower self-harm rates among young people with anxiety and depression. The research, published in, found that the risk of self-harm increased before melatonin prescriptions and decreased afterward, particularly in girls.

“Given the established link between sleep problems, depression, and self-harm, we wanted to explore whether medical sleep treatment is associated with a lower rate of intentional self-harm in young people,” says Dr. Sarah Bergen, docent at the Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, who led the study.The study identified over 25,500 children and teenagers between the ages of 6 and 18 who were prescribed melatonin in Sweden.

As it was an observational study, it cannot establish a causal relationship between melatonin and reduced self-harm rates. To check whether the use of other medications might have affected the findings, analyses were also carried out which excluded antidepressant users. The results were similar.

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