Long COVID's significant impact on health calls for greater consideration in pandemic policy planning Coronavirus Disease COVID Omicron LongCOVID Policy Medicine Health PublicHealth Epidemiology IntJEpidemiol UniMelb
By Pooja Toshniwal PahariaApr 6 2023Reviewed by Lily Ramsey, LLM In a recent study published in the International Journal of Epidemiology, researchers presented a comprehensive approach to estimating long coronavirus disease -associated morbidity in the Australian population.
Given the continual rise in SARS-CoV-2 transmission across the globe, it is critical to assess the burden of COVID-19 quantitatively and the associated long-term consequences. To precisely quantify PCC effects among COVID-19 vaccinees during Omicron predominance, differences in PCC risks by COVID-19 vaccination status and SARS-CoV-2 VOC were assessed.
The team quantified long COVID symptom severity as disability weights , reported in the global burden of disease study. Base case prevalence estimates for unvaccinated and pre-Omicron VOC-infected individuals were multiplied by an odds ratio of 0.6 to evaluate long COVID symptom prevalence among COVID-19 vaccinees.
The team performed sensitivity analyses by varying prevalence rates of physical, cognitive, and psychological symptoms. Further, an extreme case scenario was analyzed by applying the odds ratio for SARS-CoV-2 Omicron VOC vs. pre-Omicron VOC infections to hospitalized patients. The team obtained most PCC YLDs from cases in community settings, of which the majority were observed among vaccinated adults , given that the group represented 51% of the documented long COVID cases.
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