Olaparib targets cancers with BRCA 1 or BRCA 2 mutations, stopping cancer cells from being able to repair their DNA, which in turn causes the cancerous cells to die.
Around 500 men with advanced prostate cancer and some 300 women with HER2-negative early breast cancer are estimated to be eligible for the new drug each year in England.
NHS England chief executive Amanda Pritchard said:"Olaparib could have a huge impact on patients with a range of cancer types, giving many a better chance of survival while offering those with advanced forms of the disease precious extra months to live."Meanwhile, experts at the Institute of Cancer Research described the move as"life-changing", adding the treatment will give patients the chance to live longer and healthier lives.
Johann De Bono, professor in experimental cancer medicine at the ICR, said:"Olaparib is an important example of how understanding the underlying genetics of patients, and their tumours' genomics, can be used to design highly targeted precision medicines. "For patients with advanced prostate cancer and mutations in BRCA1 or BRCA2, these recommendations will be life-changing."Chiara De Biase, director of support and influencing at Prostate Cancer UK, added:"This is the first targeted treatment of its kind to be approved for the disease and it finally moves us away from the old 'one size fits all' approach to prostate cancer treatment.
"We're proud of the role we played in developing this exciting drug, which stands to extend the lives of hundreds of men each year."
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