Lab-grown mini organs promise quick vaccine testing with fewer animal trials

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Lab-grown mini organs promise quick vaccine testing with fewer animal trials
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This new vaccine testing platform can allow scientists to test vaccines faster than ever, and that too without harming numerous animal subjects.

Vaccines are life saviors but making and testing new vaccines is a complex process that mostly involves a series of animal trials. For instance, the COVID-19 vaccines were also first tested on pigs, mice, rats ferrets, non-human primates, and various other animals, and then on humans.on animals takes up a lot of time and also raises ethical concerns about the way animal subjects are treated during such trials. Well, now we have an interesting solution to this problem.

In a newly published study, a team of researchers proposes a novel vaccine screening method that uses lab-grown miniature organs to quickly test new vaccines without involving a significant number of animal models.The first coronavirus case was reported in December 2019 and by the time the first COVID-19 vaccine was approved for public use in December 2020, aboutDeveloping a vaccine suitable for human use within one year of the outbreak was a remarkable achievement.

“Hundreds of immune cell organoids can be constructed from the spleen of a single animal, greatly increasing testing throughput — which could help researchers keep up with the large numbers of compounds they can create and need to screen,” the study authors

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