Children with severe traumatic brain injury are at risk of dying or neurologic impairment. But despite decades of research, treatment options remain limited.
Ketamine induces a sense of disassociation and disembodiment. Given its dissociative effects, it is also a commonly abused recreational drug.
The children's ages ranged from 1 month to 16 years old. Twenty-two of the children received ketamine as part of a treatment protocol informed by evidence-based guidelines. "These findings suggest a potential shift in a decades-old paradigm related to ketamine and ICP," Wolf said."Not only might ketamine be an appropriate choice as a sedative medication in patients with severe TBI, in some cases it may be useful as a treatment to lower ICP when it is dangerously high."
"The stakes are high for these children, and minutes count," he said."Adding any tool to improve their care could ultimately be impactful, supporting the best possible outcomes."While the results of the latest study show promise, it is important to note that the research is preliminary and more investigations will be required before such treatments can be approved.
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