Isotopes tracked on a sub-nanometre scale using electron spectroscopy

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Isotopes tracked on a sub-nanometre scale using electron spectroscopy
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Vibrational spectroscopy for isotopic identification.

The isotopes of an atom have the same number of protons, but different numbers of neutrons. Changing the neutron count changes the mass of an atom, but it doesn’t have a pronounced effect on its chemical properties.

As a result, isotopes feature in a host of techniques used in biological and materials sciences, where they function as atomic-scale labels that can track specific compounds in heterogeneous samples and can trace chemical-reaction pathways. To make the most of isotopic labelling, isotopes must be detected with high spatial resolution.

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