Gain-of-function is a research method that involves manipulating pathogens to give them a new aspect, such as making viruses more transmissible or dangerous to humans.
over whether experiments done on bat coronaviruses conducted at the Wuhan Institute of Virology constituted gain of function research.
"If you started with a bat virus that could not infect human cells and then gave it the ability to do so, that would be a gain-of-function. But that is not what they did there," Racaniello said."They didn't give it a new property." During Tuesday's hearing, Paul argued the work did constituted gain-of-function because they created"novel, artificial viruses" that could infect humans out of animal viruses." He cited an article that quoted Richard Ebright, a chemistry and chemical biology professor at Rutgers University, saying the experiment"epitomizes" gain-of-function research.
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