'It was called a monster breakthrough, the biggest advance in the pandemic since the vaccines.'
, a reporter for the Atlantic, about the mysteries of Paxlovid. Our conversation has been edited and condensed for clarity.
There was an Israeli study about a month and a half ago that looked at both vaccinated and unvaccinated people, and it was, crucially, done during the omicron era. The Pfzier trial was conducted pretty much completely in the delta era. So some of the difference, the daylight between the amazing results in the high risk trial and the not as great results in the standard risk trial could also have something to do with the variant.
I would say that rebound is when you have taken Paxlovid, you’ve finished your course, your symptoms have abated, you test negative—and then within a few days you get a reversal. You test positive again, your symptoms come back.
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