Intravascular imaging-guided PCI associated with lower rate of target lesion failure

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Intravascular imaging-guided PCI associated with lower rate of target lesion failure
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Intravascular imaging-guided percutaneous coronary intervention (PCI) is associated with a lower rate of target lesion failure compared with angiography-guided PCI, according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

Numerous randomized trials have compared intravascular imaging-guided PCI with angiography-guided PCI. However, most of these prior trials have used intravascular ultrasound . Optical coherence tomography is a newer intravascular imaging modality that has enhanced resolution compared to IVUS.

The analysis incorporated 20 randomized trials of intravascular imaging-guided PCI compared with angiography-guided PCI in 12,428 patients with chronic and acute coronary syndromes. Of those, 7,038 were randomly allocated to intravascular imaging guidance , and 5,390 patients were randomly allocated to angiography guidance. Patients were followed for between 6 months and 5 years.

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