Insights into the direction and extent of gut microbiome dysbiosis in Alzheimer’s disease and mild cognitive impairment PLOSONE microbiome gut gutmicrobiome Alzheimers disease Alzheimersdisease
By Pooja Toshniwal PahariaMay 26 2023Reviewed by Danielle Ellis, B.Sc. In a recent study published in PLOS ONE, researchers performed a meta-analysis to determine the association between intestinal microbiota and Alzheimer’s disease .
About the study In the present meta-analysis, researchers reported on the contribution of gut microbes to Alzheimer’s disease and associated mild cognitive impairments. The primary study outcomes were altered alpha-diversity and microbial taxa abundance, analyzed by inverse variance-weighted random-effects modeling. The secondary study outcomes emphasized linear discriminant analysis effect sizes and qualitative beta-diversity ordination. Bias risks were evaluated using suitable methods for the study types, and subgroups were analyzed in the case of considerable heterogeneity in the included studies.
Related StoriesThe findings indicated that location, lifestyle, and diet considerably impact the intestinal microflora and the pathogenesis of AD. Further, Phascolarctobacterium species increased significantly only in the initial stage of mild cognitive impairment.
Österreich Neuesten Nachrichten, Österreich Schlagzeilen
Similar News:Sie können auch ähnliche Nachrichten wie diese lesen, die wir aus anderen Nachrichtenquellen gesammelt haben.
Clinical trials are vital to science, yet researchers keep moving the goalpostsClinical trials are vital to science, yet researchers keep moving the goalposts 📨 Read StuartJRitchie's latest newsletter
Weiterlesen »
Investigating the interplay between white blood cell count and incidence of hyper-low-density lipoprotein cholesterolemiaInvestigating the interplay between white blood cell count and incidence of hyper-low-density lipoprotein cholesterolemia SciReports whitebloodcell WBC cellcount LDL hyperLDL cholesterol cholesteremia
Weiterlesen »
The adaptive immunity of human endemic virusesThe adaptive immunity of human endemic viruses biorxivpreprint immunity immunology virology human endemic virus viruses endemicvirus
Weiterlesen »
Keto vs. low-fat diets: which is more sustainable in the long term?Keto vs. low-fat diets: which is more sustainable in the long term? UPR_Oficial keto highfatdiet lowcarbdiet highcarbdiet lowfatdiet ketogenic ketodiet diet nutrition health
Weiterlesen »
Adoption of Mediterranean diet shows promise in easing symptoms for myeloproliferative neoplasm patientsAdoption of Mediterranean diet shows promise in easing symptoms for myeloproliferative neoplasm patients ChronicInflammation MPN Pathogenesis MediterraneanDiet DietIntervention InflammatoryBiomarkers Gut Microbiome Nutrition medrxivpreprint
Weiterlesen »
New review unravels phthalates’ role in heart diseaseNew review unravels phthalates’ role in heart disease Phthalates HeartDisease Cardiology Heart
Weiterlesen »