Nature research paper: Inhibition of ASGR1 decreases lipid levels by promoting cholesterol excretion
. Fifty-six hours after transfection, cells were switched to DMEM containing 10% FBS or cholesterol depletion medium. After 16 h, cells were harvested, lysed and subjected to immunoblotting., Huh7 cells were transfected with indicated plasmids. Thirty-two hours after transfection, cells were switched to DMEM containing 10% FBS or cholesterol depletion medium. After 16 h, cells were harvested, lysed, and subjected to immunoblotting.did not influence Dil-LDL uptake.
The internalized Dil-LDL in WT cells at 0 h is defined as 0 .did not change the PCSK9-induced LDLR degradation. Huh7 cells were transfected with indicated siRNA. The cells were incubated in DMEM containing 10% FBS or cholesterol depletion medium for 12 h. The cells were treated with indicated amounts of PCSK9 protein for additional 4 h.mice were fed an HF/HC/BS diet for 2 days. Before measuring the uptake rate, the mice were fasted for 17 h and refed for 6 h.
Österreich Neuesten Nachrichten, Österreich Schlagzeilen
Similar News:Sie können auch ähnliche Nachrichten wie diese lesen, die wir aus anderen Nachrichtenquellen gesammelt haben.
Nature’s Flower Show: Check Out the Swamp Rose Mallow at Sand Ridge Nature CenterThe native swamp rose mallow has hit full bloom, its super-sized six-inch blossoms bursting forth in seemingly every shade of pink from the palest blush to saturated fuschia
Weiterlesen »
N.J. reports 2,627 COVID cases, 17 deaths; daily cases and deaths remain highNew Jersey's seven-day average is 2,689, a 7% decrease in the past week.
Weiterlesen »
LA County’s COVID-19 Cases Are DroppingNew COVID-19 infections are on the way down in Los Angeles County, dropping by 28% since the peak in July, according to the County Department of Public Health.
Weiterlesen »
Airfare prices finally dropping from summer's record high pricesThe average roundtrip for flights is expected to fall to $286, which would be down 25% compared to the peak we saw in May.
Weiterlesen »
Like Humans, Chimpanzees Talk to Coordinate Cooperative HuntsCooperation and communication — two hallmarks of human nature — likely arose early in primate evolution.
Weiterlesen »
Saban calls last season 'a rebuilding year'Let’s take a moment to consider the relative nature of things.
Weiterlesen »